Novedades Condroprotección

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Apreciado/a Dr/a Victor Manuel Valdes 5 de junio de 2013 A continuación le mostramos las novedades de las revistas más importantes en Condroprotección.
	Lesiones focales de rodilla en sujetos sintomáticos y asintomáticos con factores de riesgo de artrosis - Datos procedentes de la Osteoarthritis Initiative     Eur J Radiol. 2013 Mar 26. pii: S0720-048X(13)00129-0. doi: 10.1016/j.ejrad.2013.02.038. [publicación electrónica previa a la publicación impresa]     Factores predictivos del dolor postquirúrgico agudo y de la ansiedad tras una artroplastia primaria total de cadera y rodilla     J Pain 2013 Mar 27. pii: S1526-5900(13)00035-7. doi: 10.1016/j.jpain.2012.12.020. [publicación electrónica previa a la publicación impresa]   Annals of the Rheumatic Diseases June 2013, Volume 72, Issue 6 MRI comes of age in RA clinical trials Charles Peterfy, Mikkel Østergaard, Philip G Conaghan   Whipple’s disease Xavier Puéchal   EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis Alexandra N Colebatch, Christopher John Edwards, Mikkel Østergaard, Désirée van der Heijde, Peter V Balint, Maria-Antonietta D’Agostino, Kristina Forslind, Walter Grassi,Espen A Haavardsholm, Glenn Haugeberg, Anne-Grethe Jurik, Robert BM Landewé,Esperanza Naredo, Philip J O’Connor, Ben Ostendorf, Kristina Potočki, Wolfgang A Schmidt, Josef S Smolen, Sekib Sokolovic, Iain Watt, Philip G Conaghan   Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: results of a randomised placebo-controlled trial (ABILITY-1) Joachim Sieper, Désirée van der Heijde, Maxime Dougados, Philip J Mease, Walter P Maksymowych, Matthew A Brown, Vipin Arora, Aileen L Pangan   Similar response rates in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis after 1 year of treatment with etanercept: results from the ESTHER trial In-Ho Song, Anja Weiß, Kay-Geert A Hermann, Hildrun Haibel, Christian E Althoff, Denis Poddubnyy, Joachim Listing, Ekkehard Lange, Bruce Freundlich, Martin Rudwaleit, Joachim Sieper   Patients with gout adhere to curative treatment if informed appropriately: proof-of-concept observational study Frances Rees, Wendy Jenkins, M Doherty   Patients' needs and expectations with regard to rheumatology nursing care: results of multicentre focus group interviews Yvonne van Eijk-Hustings, Judy Ammerlaan, Hanneke Voorneveld-Nieuwenhuis, Bertha Maat, Conny Veldhuizen, Han Repping-Wuts   Patient satisfaction with nursing consultations in a rheumatology outpatient clinic: a 21-month randomised controlled trial in patients with inflammatory arthritides Hege Svean Koksvik, Kåre Birger Hagen, Erik Rødevand, Petter Mowinckel, Tore K Kvien,Heidi A Zangi   Induction therapy with adalimumab plus methotrexate for 24 weeks followed by methotrexate monotherapy up to week 48 versus methotrexate therapy alone for DMARD-naïve patients with early rheumatoid arthritis: HIT HARD, an investigator-initiated study Jacqueline Detert, Hans Bastian, Joachim Listing, Anja Weiß, Siegfried Wassenberg,Anke Liebhaber, Karin Rockwitz, Rieke Alten, Klaus Krüger, Rolf Rau, Christina Simon,Eva Gremmelsbacher, Tanja Braun, Bettina Marsmann, Vera Höhne-Zimmer, Karl Egerer, Frank Buttgereit, Gerd-R Burmester   Infliximab for 6 months added on combination therapy in early rheumatoid arthritis: 2-year results from an investigator-initiated, randomised, double-blind, placebo-controlled study (the NEO-RACo Study) Marjatta Leirisalo-Repo, Hannu Kautiainen, Leena Laasonen, Markku Korpela, Markku J Kauppi, Oili Kaipiainen-Seppänen, Riitta Luosujärvi, Reijo Luukkainen, Anna Karjalainen,Harri Blåfield, Toini Uutela, Kirsti Ilva, Heikki A Julkunen, Leena Paimela, Kari Puolakka,Eeva Moilanen, Pekka J Hannonen, Timo Möttönen, for the NEO-RACo Study Group   Very early rheumatoid arthritis as a predictor of remission: a multicentre real life prospective study Elisa Gremese, Fausto Salaffi, Silvia Laura Bosello, Alessandro Ciapetti, Francesca Bobbio-Pallavicini, Roberto Caporali, Gianfranco Ferraccioli   Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study Mark C Genovese, Patrick Durez, Hanno B Richards, Jerzy Supronik, Eva Dokoupilova,Vadim Mazurov, Jacob A Aelion, Sang-Heon Lee, Christine E Codding, Herbert Kellner,Takashi Ikawa, Sophie Hugot, Shephard Mpofu   'Insights in the relationship of joint space narrowing versus erosive joint damage and physical functioning of patients with RA' R Koevoets, L Dirven, N B Klarenbeek, M V van Krugten, H K Ronday, D M F M van der Heijde, T W J Huizinga, P S J M Kerstens, W F Lems, C F Allaart   Rheumatoid factor determines structural progression of rheumatoid arthritis dependent and independent of disease activity Daniel Aletaha, Farideh Alasti, Josef S Smolen   Etanercept normalises left ventricular mass in patients with rheumatoid arthritis Claire Immediato Daïen, Pierre Fesler, Guilhem du Cailar, Vincent Daïen, Thibault Mura,Anne-Marie Dupuy, Jean-Paul Cristol, Jean Ribstein, Bernard Combe, Jacques Morel   Ambient air pollution exposures and risk of rheumatoid arthritis: results from the Swedish EIRA case-control study Jaime E Hart, Henrik Källberg, Francine Laden, Tom Bellander, Karen H Costenbader,Marie Holmqvist, Lars Klareskog, Lars Alfredsson, Elizabeth W Karlson   Difference in the risk of serious infections in patients with rheumatoid arthritis treated with adalimumab, infliximab and etanercept: results from the Dutch Rheumatoid Arthritis Monitoring (DREAM) registry Sanne A A van Dartel, Jaap Fransen, Wietske Kievit, Marcel Flendrie, Alfons A den Broeder, H Visser, A Hartkamp, Mart A F J van de Laar, Piet L C M van Riel   Multiple cytokines and chemokines are associated with rheumatoid arthritis-related autoimmunity in first-degree relatives without rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA) Jan M Hughes-Austin, Kevin D Deane, Lezlie A Derber, Jason R Kolfenbach, Gary O Zerbe, Jeremy Sokolove, Lauren J Lahey, Michael H Weisman, Jane H Buckner, Ted R Mikuls, James R O’Dell, Richard M Keating, Peter K Gregersen, William H Robinson, V Michael Holers, Jill M Norris   Methotrexate polyglutamation in relation to infliximab pharmacokinetics in rheumatoid arthritis Thierry Dervieux, Michael E Weinblatt, Alan Kivitz, Joel M Kremer   An increased rate of falling leads to a rise in fracture risk in postmenopausal women with self-reported osteoarthritis: a prospective multinational cohort study (GLOW) Daniel Prieto-Alhambra, Xavier Nogues, M Kassim Javaid, Allison Wyman, Nigel K Arden,Rafael Azagra, Cyrus Cooper, Jonathan D Adachi, Steven Boonen, Roland D Chapurlat,Juliet E Compston, Stephen H Gehlbach, Susan L Greenspan, Frederick H Hooven, J Coen Netelenbos, Johannes Pfeilschifter, Maurizio Rossini, Philip N Sambrook, Stuart Silverman, Ethel S Siris, Nelson B Watts, Adolfo Díez-Pérez   Cam impingement causes osteoarthritis of the hip: a nationwide prospective cohort study (CHECK) Rintje Agricola, Marinus P Heijboer, Sita M A Bierma-Zeinstra, Jan A N Verhaar, Harrie Weinans, Jan H Waarsing   Progression of osteoarthritis as a state of inertia David Felson, Jingbo Niu, Burton Sack, Piran Aliabadi, Charles McCullough, Michael C Nevitt   In erosive hand osteoarthritis more inflammatory signs on ultrasound are found than in the rest of hand osteoarthritis Marion C Kortekaas, Wing-Yee Kwok, Monique Reijnierse, Tom W J Huizinga, Margreet Kloppenburg   Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data Katherine S Elliott, Kay Chapman, Aaron Day-Williams, Kalliope Panoutsopoulou,Lorraine Southam, Cecilia M Lindgren, Nigel Arden, Nadim Aslam, Fraser Birrell, Ian Carluke, Andrew Carr, Panos Deloukas, Michael Doherty, John Loughlin, Andrew McCaskie, William E R Ollier, Ashok Rai, Stuart Ralston, Mike R Reed, Timothy D Spector, Ana M Valdes, Gillian A Wallis, Mark Wilkinson, Eleftheria Zeggini   Co-localisation of non-cartilaginous articular pathology increases risk of cartilage loss in the tibiofemoral joint-the MOST study Frank W Roemer, David T Felson, Ke Wang, Michel D Crema, Tuhina Neogi, Yuqing Zhang, Michael C Nevitt, Monica D Marra, Cora E Lewis, James Torner, Ali Guermazi, for MOST study investigators   Incidence and predictors of secondary fibromyalgia in an early arthritis cohort Yvonne C Lee, Bing Lu, Gilles Boire, Boulos (Paul) Haraoui, Carol A Hitchon, Janet E Pope, J Carter Thorne, Edward Clark Keystone, Daniel H Solomon, Vivian P Bykerk   Comparative efficacy of pharmacological and non-pharmacological interventions in fibromyalgia syndrome: network meta-analysis Eveline Nüesch, Winfried Häuser, Kathrin Bernardy, Jürgen Barth, Peter Jüni   Muscle fatigue in fibromyalgia is in the brain, not in the muscles: a case-control study of perceived versus objective muscle fatigue Elisabeth Bandak, Kirstine Amris, Henning Bliddal, Bente Danneskiold-Samsøe, Marius Henriksen   Active inflammation and structural change in early active axial spondyloarthritis as detected by whole-body MRI Christian E Althoff, Joachim Sieper, In-Ho Song, Hildrun Haibel, Anja Weiß, Torsten Diekhoff, Martin Rudwaleit, Bruce Freundlich, Bernd Hamm, Kay-Geert A Hermann   Epistasis between two HLA antigens defines a subset of individuals at a very high risk for ankylosing spondylitis Floris A van Gaalen, Willem Verduijn, Dave L Roelen, Stefan Böhringer, Tom W J Huizinga, Désirée M van der Heijde, René E M Toes   Does the site of magnetic resonance imaging abnormalities match the site of recent-onset inflammatory back pain? The DESIR cohort Martin Blachier, Bertrand Coutanceau, Maxime Dougados, Alain Saraux, Sylvie Bastuji-Garin, Salah Ferkal, Philippe Le Corvoisier, Valérie Farrenq, Cécile Poulain, Bijan Ghaleh, Florence Canouï-Poitrine, Pascal Claudepierre   The development of candidate composite disease activity and responder indices for psoriatic arthritis (GRACE project) Philip S Helliwell, Oliver FitzGerald, Jaap Fransen, Dafna D Gladman, Gerald G Kreuger,Kristina Callis-Duffin, Neil McHugh, Philip J Mease, Vibeke Strand, Robin Waxman,Valderilio Feijo Azevedo, Adriana Beltran Ostos, Sueli Carneiro, Alberto Cauli, Luis R Espinoza, John A Flynn, Nada Hassan, Paul Healy, Eduardo Mario Kerzberg, Yun Jong Lee, Ennio Lubrano, Antonio Marchesoni, Helena Marzo-Ortega, Giovanni Porru, Elvia G Moreta, Peter Nash, Helena Raffayova, Roberto Ranza, Siba P Raychaudhuri, Euthalia Roussou, Raphael Scarpa, Yeong Wook Song, Enrique R Soriano, Paul P Tak, Ilona Ujfalussy, Kurt de Vlam, Jessica A Walsh   The link between enthesitis and arthritis in psoriatic arthritis: a switch to a vascular phenotype at insertions may play a role in arthritis development Sibel Z Aydin, Zoe R Ash, Ilaria Tinazzi, Concepción Castillo-Gallego, Chung Kwok,Caroline Wilson, Mark Goodfield, Paolo Gisondi, Ai Lyn Tan, Helena Marzo-Ortega, Paul Emery, Richard J Wakefield, Dennis G McGonagle   Steroid injection for inferior heel pain: a randomised controlled trial Alfred Mahr, Sandrine Katsahian, Hugo Varet, Loïc Guillevin, E Christiaan Hagen, Peter Höglund, Peter A Merkel, Christian Pagnoux, Niels Rasmussen, Kerstin Westman, David R W Jayne, for the French Vasculitis Study Group (FVSG) and the European Vasculitis Society (EUVAS)   A vasculitis centre based management strategy leads to improved outcome in eosinophilic granulomatosis and polyangiitis (Churg-Strauss, EGPA): monocentric experiences in 150 patients Frank Moosig, Jan Phillip Bremer, Bernhard Hellmich, Julia Ulrike Holle, Konstanze Holl-Ulrich, Martin Laudien, Christine Matthis, Claudia Metzler, Bernhard Nölle, Gert Richardt,Wolfgang L Gross   HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus Emeli Lundström, Johanna T Gustafsson, Andreas Jönsen, Dag Leonard, Agneta Zickert, Kerstin Elvin, Gunnar Sturfelt, Gunnel Nordmark, Anders A Bengtsson, Ulf Sundin, Henrik Källberg, Johanna K Sandling, Ann-Christine Syvänen, Lars Klareskog,Iva Gunnarsson, Lars Rönnblom, Leonid Padyukov, Elisabet Svenungsson   Efficacy of rituximab in systemic manifestations of primary Sjögren’s syndrome: results in 78 patients of the AutoImmune and Rituximab registry Jacques-Eric Gottenberg, Gael Cinquetti, Claire Larroche, Bernard Combe, Eric Hachulla, Olivier Meyer, Edouard Pertuiset, Guy Kaplanski, Laurent Chiche, Jean-Marie Berthelot, Bruno Gombert, Philippe Goupille, Christian Marcelli, Séverine Feuillet, Jean Leone, Jean Sibilia, Charles Zarnitsky, Philippe Carli, Stephanie Rist, Philippe Gaudin,Carine Salliot, Muriel Piperno, Adeline Deplas, Maxime Breban, Thierry Lequerre, Pascal Richette, Charles Ghiringhelli, Mohamed Hamidou, Philippe Ravaud, Xavier Mariette   Progression to rheumatoid arthritis in early inflammatory arthritis is associated with low IL-7 serum levels Vincent Goëb, Philippe Aegerter, Rekha Parmar, Patrice Fardellone, Oliver Vittecoq, Philip G Conaghan, Paul Emery, Xavier Le Loët, Frédérique Ponchel   Anti-TNF treatment blocks the induction of T cell-dependent humoral responses Gabriela Franco Salinas, Leen De Rycke, Barbara Barendregt, Jacqueline E Paramarta,Hulda Hreggvidstdottir, Tineke Cantaert, Mirjam van der Burg, Paul P Tak, Dominique Baeten   Autophagy contributes to inflammation in patients with TNFR-associated periodic syndrome (TRAPS) Tiziana Bachetti, Sabrina Chiesa, Patrizio Castagnola, Daniele Bani, Eleonora Di Zanni,Alessia Omenetti, Andrea D’Osualdo, Alessandro Fraldi, Andrea Ballabio, Roberto Ravazzolo, Alberto Martini, Marco Gattorno, Isabella Ceccherini   Granulocyte colony stimulating factor exacerbates antineutrophil cytoplasmic antibody vasculitis Simon J Freeley, Alice M Coughlan, Reena J Popat, Deborah K Dunn-Walters, Michael G Robson   The concentration of anticitrullinated protein antibodies in serum and synovial fluid in relation to total immunoglobulin concentrations Annemiek Willemze, Jing Shi, Marlies Mulder, Gerrie Stoeken-Rijsbergen, Jan W Drijfhout, Tom W J Huizinga, Leendert A Trouw, Rene E M Toes   Microarray-based gene expression profiling in patients with cryopyrin-associated periodic syndromes defines a disease-related signature and IL-1-responsive transcripts James E Balow, Jr, John G Ryan, Jae Jin Chae, Matthew G Booty, Ariel Bulua, Deborah Stone, Hong-Wei Sun, James Greene, Beverly Barham, Raphaela Goldbach-Mansky,Daniel L Kastner, Ivona Aksentijevich   MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes Lucas Philippe, Ghada Alsaleh, Angélique Pichot, Eleonore Ostermann, Guy Zuber,Benoit Frisch, Jean Sibilia, Sébastien Pfeffer, Seiamak Bahram, Dominique Wachsmann, Philippe Georgel   Notch signalling pathways mediate synovial angiogenesis in response to vascular endothelial growth factor and angiopoietin 2 Wei Gao, Catherine Sweeney, Ceara Walsh, Peadar Rooney, Jennifer McCormick,Douglas J Veale, Ursula Fearon   Critical role of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of inflammation-driven dermal fibrosis in a mouse model of systemic sclerosis Jérôme Avouac, Muriel Elhai, Michal Tomcik, Barbara Ruiz, Manuel Friese, Melanie Piedavent, Marco Colonna, Gunter Bernhardt, André Kahan, Gilles Chiocchia, Jörg H W Distler, Yannick Allanore   Revisiting the classification of clinical phenotypes of anti-neutrophil cytoplasmic antibody-associated vasculitis: a cluster analysis Alfred Mahr, Sandrine Katsahian, Hugo Varet, Loïc Guillevin, E Christiaan Hagen, Peter Höglund, Peter A Merkel, Christian Pagnoux, Niels Rasmussen, Kerstin Westman, David R W Jayne, for the French Vasculitis Study Group (FVSG) and the European Vasculitis Society (EUVAS)   Arthritis & Rheumatism Volume 65, Issue 6, June 2013 Changes in lipoproteins associated with treatment with methotrexate or combination therapy in early rheumatoid arthritis: Results from the TEAR trial  Iris Navarro-Millán, Christina Charles-Schoeman, Shuo Yang, Joan M. Bathon, S. Louis Bridges Jr., Lang Chen, Stacey S. Cofield, Louis J. Dell'Italia, Larry W. Moreland, James R. O'Dell, Harold E. Paulus and Jeffrey R. Curtis   Anti-Citrullinated Protein Antibodies in Unaffected First-Degree Relatives of Rheumatoid Arthritis Patients Lillian Barra, Mathias Scinocca, Sheri Saunders, Rajesh Bhayana, Sherry Rohekar, Maud Racapé, Robert Coles, Ewa Cairns and David A. Bell   Metabolic Profiling Predicts Response to Anti-Tumor Necrosis Factor α Therapy in Patients With Rheumatoid Arthritis Sabrina R. Kapoor, Andrew Filer, Martin A. Fitzpatrick, Benjamin A. Fisher, Peter C. Taylor, Christopher D. Buckley, Iain B. McInnes, Karim Raza and Stephen P. Young   Rheumatoid Arthritis in Latin Americans Enriched for Amerindian Ancestry is Associated With Loci in Chromosomes 1, 12, and 13, and the HLA Class II Region David López Herráez, Manuel Martínez-Bueno, Laura Riba, Ignacio García de la Torre, Mónica Sacnún, Mario Goñi, Guillermo A. Berbotto, Sergio Paira, Jorge Luis Musuruana, César E. Graf, Alejandro J. Alvarellos, Osvaldo D. Messina, Alejandra M. Babini, Ingrid Strusberg, Juan Carlos Marcos, Hugo Scherbarth, Alberto J. Spindler, Ana Quinteros, Sergio M. A. Toloza, José Luis C. Moreno, Luis J. Catoggio, Guillermo Tate, Alicia Eimon, Gustavo Citera, Antonio Catalán Pellet, Gustavo G. Nasswetter, Mario H. Cardiel, Pedro Miranda, Francisco Ballesteros, Jorge A. Esquivel-Valerio, Marco A. Maradiaga-Ceceña, Eduardo M. Acevedo-Vásquez, Conrado García García, Bernardo A. Pons-Estel and Marta E. Alarcón-Riquelme, GEMAR Study Collaborators Teresa Tusié-Luna   Tumor Necrosis Factor Receptor Type I Expression of CD4+ T Cells in Rheumatoid Arthritis Enables Them to Follow Tumor Necrosis Factor Gradients Into the Rheumatoid Synovium Manuela Rossol, Kristin Schubert, Undine Meusch, Anett Schulz, Bernd Biedermann, Jens Grosche, Matthias Pierer, Roger Scholz, Christoph Baerwald, Andreas Thiel, Sebastian Hagen and Ulf Wagner   Testosterone Is Protective in the Sexually Dimorphic Development of Arthritis and Lung Disease in SKG Mice Rebecca C. Keith, Jeremy Sokolove, Benjamin L. Edelman, Lauren Lahey, Elizabeth F. Redente, V. Michael Holers, Shimon Sakaguchi, William H. Robinson and David W. H. Riches   Neuropathic Pain in Ankylosing Spondylitis: A Psychophysics and Brain Imaging Study Qi Wu, Robert D. Inman and Karen D. Davis   Reduced Joint Counts Misclassify Patients With Oligoarticular Psoriatic Arthritis and Miss Significant Numbers of Patients With Active Disease Laura C. Coates, Oliver FitzGerald, Dafna D. Gladman, Neil McHugh, Philip Mease, Vibeke Strand and Philip S. Helliwell, GRACE Collaboration   Combinatorial Control of Th17 and Th1 Cell Functions by Genetic Variations in Genes Associated With the Interleukin-23 Signaling Pathway in Spondyloarthritis Maryaline Coffre, Mathilde Roumier, Magda Rybczynska, Emmanuel Sechet, Helen K. W. Law, Laure Gossec, Maxime Dougados, Elisabetta Bianchi and Lars Rogge   In Situ Analysis of Interleukin-23- and Interleukin-12-Positive Cells in the Spine of Patients With Ankylosing Spondylitis Heiner Appel, Rene Maier, Janine Bleil, Axel Hempfing, Christoph Loddenkemper, Uwe Schlichting, Uta Syrbe and Joachim Sieper   MicroRNA-29a Protects Against Glucocorticoid-Induced Bone Loss and Fragility in Rats by Orchestrating Bone Acquisition and Resorption Feng-Sheng Wang, Pei-Chin Chung, Chung-Liang Lin, Ming-Wen Chen, Huei-Jin Ke, Yu-Hsuan Chang, Yu-Shan Chen, Shin-Long Wu and Jih-Yang Ko   Relationship of Bone Mineral Density to Progression of Knee Osteoarthritis Ji Y. Lee, William F. Harvey, Lori L. Price, Jessica K. Paulus, Bess Dawson-Hughes and Timothy E. McAlindon   Transcriptomics of Wild-Type Mice and Mice Lacking ADAMTS-5 Activity Identifies Genes Involved in Osteoarthritis Initiation and Cartilage Destruction John F. Bateman, Lynn Rowley, Daniele Belluoccio, Ben Chan, Katrina Bell, Amanda J. Fosang and Christopher B. Little   Rac1 Is Required for Matrix Metalloproteinase 13 Production by Chondrocytes in Response to Fibronectin Fragments David L. Long, Jeffrey S. Willey and Richard F. Loeser   In Vivo Cyclic Compression Causes Cartilage Degeneration and Subchondral Bone Changes in Mouse Tibiae Frank C. Ko, Cecilia Dragomir, Darren A. Plumb, Steven R. Goldring, Timothy M. Wright, Mary B. Goldring and Marjolein C. H. van der Meulen   A Hot Spot for Systemic Lupus Erythematosus, but Not for Psoriatic Arthritis, Identified by Spatial Analysis Suggests an Interaction Between Ethnicity and Place of Residence Mustafa Al-Maini, Thurarshen Jeyalingam, Patrick Brown, Jennifer J. Y. Lee, Lennon Li, Jiandong Su, Dafna D. Gladman and Paul R. Fortin   Comparison of Alternative Primary Outcome Measures for Use in Lupus Nephritis Clinical Trials David Wofsy, Jan L. Hillson and Betty Diamond   Enhanced Rho-Associated Protein Kinase Activation in Patients With Systemic Lupus Erythematosus Josephine Isgro, Sanjay Gupta, Elzbieta Jacek, Tanya Pavri, Roland Duculan, Mimi Kim, Kyriakos A. Kirou, Jane E. Salmon and Alessandra B. Pernis   MicroRNA-30a Promotes B Cell Hyperactivity in Patients With Systemic Lupus Erythematosus by Direct Interaction With Lyn Yu Liu, Jie Dong, Rong Mu, Yaping Gao, Xiaorong Tan, Yuhui Li, Zhanguo Li and Guang Yang   Toll-like Receptor 2 Is Required for Autoantibody Production and Development of Renal Disease in Pristane-Induced Lupus Vilma Urbonaviciute, Charlotte Starke, Wiebke Pirschel, Sandy Pohle, Silke Frey, Christoph Daniel, Kerstin Amann, Georg Schett, Martin Herrmann and Reinhard E. Voll   FTY720 Ameliorates Murine Sclerodermatous Chronic Graft-Versus-Host Disease by Promoting Expansion of Splenic Regulatory Cells and Inhibiting Immune Cell Infiltration Into Skin Doanh Le Huu, Takashi Matsushita, Guihua Jin, Yasuhito Hamaguchi, Minoru Hasegawa, Kazuhiko Takehara and Manabu Fujimoto   Clinically Insignificant Effect of Supplemental Vitamin C on Serum Urate in Patients With Gout: A Pilot Randomized Controlled Trial Lisa K. Stamp, John L. O’Donnell, Christopher Frampton, Jill M. Drake, Mei Zhang and Peter T. Chapman   Dysregulation of CD4+CD25high T Cells in the Synovial Fluid of Patients With Antibiotic-Refractory Lyme Arthritis Nalini K. Vudattu, Klemen Strle, Allen C. Steere and Elise E. Drouin   Familial Mediterranean Fever in Heterozygotes: Are We Able to Accurately Diagnose the Disease in Very Young Children? Véronique Hentgen, Gilles Grateau, Katia Stankovic-Stojanovic, Serge Amselem and Isabelle Jéru   Susceptibility to Childhood-Onset Rheumatoid Arthritis: Investigation of a Weighted Genetic Risk Score That Integrates Cumulative Effects of Variants at Five Genetic Loci Sampath Prahalad, Karen N. Conneely, Yunxuan Jiang, Marc Sudman, Carol A. Wallace, Milton R. Brown, Lori A. Ponder, Mina Rohani-Pichavant, Michael E. Zwick, David J. Cutler, Sheila T. Angeles-Han, Larry B. Vogler, Christine Kennedy, Kelly Rouster-Stevens, Carol A. Wise, Marilynn Punaro, Ann M. Reed, Elizabeth D. Mellins, John F. Bohnsack, David N. Glass and Susan D. Thompson   Osteoarthritis and Cartilage Volume 21, Issue 6, Pages 783-888 (June 2013)  Associations between radiographic lumbar spinal stenosis and clinical symptoms in the general population: the Wakayama Spine Study  Y. Ishimoto, N. Yoshimura, S. Muraki, H. Yamada, K. Nagata, H. Hashizume, N. Takiguchi, A. Minamide, H. Oka, H. Kawaguchi, K. Nakamura, T. Akune, M. Yoshida   Physical activity, alignment and knee osteoarthritis: data from MOST and the OAI  D.T. Felson, J. Niu, T. Yang, J. Torner, C.E. Lewis, P. Aliabadi, B. Sack, L. Sharma, A. Guermazi, J. Goggins, M.C. Nevitt, MOST and OAI investigators   Regional variation in T1ρ and T2 times in osteoarthritic human menisci: correlation with mechanical properties and matrix composition  M. Son, S.B. Goodman, W. Chen, B.A. Hargreaves, G.E. Gold, M.E. Levenston   A rapid, novel method of volumetric assessment of MRI-detected subchondral bone marrow lesions in knee osteoarthritis  C. Ratzlaff, A. Guermazi, J. Collins, J.N. Katz, E. Losina, C. Vanwyngaarden, R. Russell, T. Iranpour, J. Duryea   Diagnostic and prognostic value of bone biomarkers in progressive knee osteoarthritis: a 6-year follow-up study in middle-aged subjects  J. Kumm, A. Tamm, M. Lintrop, A. Tamm   Skin pentosidine in very early hip/knee osteoarthritis (CHECK) is not a strong independent predictor of radiographic progression over 5 years follow-up  P.A.J.M. Vos, P.M.J. Welsing, J. deGroot, A.M. Huisman, J.C.M. Oostveen, M. Reijman, J. Damen, S.C. Mastbergen, F.P.J.G. Lafeber   Relationship between pre-radiographic cartilage damage following anterior cruciate ligament injury and biomarkers of cartilage turnover in clinical practice: a cross-sectional observational study  H. Yoshida, T. Kojima, K. Kurokouchi, S. Takahashi, H. Hanamura, M. Kojima, A.R. Poole, N. Ishiguro   Reproductive status and sex show strong effects on knee OA in a baboon model  T.E. Macrini, H.B. Coan, S.M. Levine, T. Lerma, C.D. Saks, D.J. Araujo, T.L. Bredbenner, R.D. Coutts, D.P. Nicolella, L.M. Havill   Stereological analysis of subchondral angiogenesis induced by chitosan and coagulation factors in microdrilled articular cartilage defects  C. Mathieu, A. Chevrier, V. Lascau-Coman, G.E. Rivard, C.D. Hoemann   Microstructural remodeling of articular cartilage following defect repair by osteochondral autograft transfer  C.B. Raub, S.C. Hsu, E.F. Chan, R. Shirazi, A.C. Chen, E. Chnari, E.J. Semler, R.L. Sah   The matrilin-3 VWA1 domain modulates interleukin-6 release from primary human chondrocytes  A.R. Klatt, B. Paul-Klausch, G. Klinger, U. Hillebrand, G. Kühn, B. Kobbe, J.H. Renno, W. Johannis, M. Paulsson, R. Wagener   Effect of hypoxia/reoxygenation on the cytokine-induced production of nitric oxide and superoxide anion in cultured osteoarthritic synoviocytes  C. Chenevier-Gobeaux, C. Simonneau, H. Lemarechal, D. Bonnefont-Rousselot, S. Poiraudeau, F. Rannou, O.G. Ekindjian, P. Anract, D. Borderie   Real-time assessment of bone metabolism in small animal models for osteoarthritis using multi pinhole-SPECT/CT  T.M. Piscaer, M. Sandker, O.P. van der Jagt, J.A.N. Verhaar, M. de Jong, H. Weinans   Journal of Clinical Rheumatology June 2013 - Volume 19 - Issue 4 MDHAQ/RAPID3 to Recognize Improvement Over 2 Months in Usual Care of Patients With Osteoarthritis, Systemic Lupus Erythematosus, Spondyloarthropathy, and Gout, as Well as Rheumatoid Arthritis Castrejón, Isabel; Bergman, Martin J.; Pincus, Theodore   Assessing Process of Care in Rheumatoid Arthritis at McGill University Hospitals Li, Lisa Marina; Tessier-Cloutier, Basile; Wang, Yafei; Bernatsky, Sasha; Vinet, Evelyne; Ménard, Henri André; Panopalis, Pantelis; Hazel, Elizabeth; Stein, Michael; Cohen, Martin; Starr, Michael; Pineau, Christian; Veilleux, Marie-ève; Colmegna, Inés   Association Between Adverse Reactions to Allopurinol and Exposures to High Maintenance Doses: Implications for Management of Patients Using Allopurinol Paisansinsup, Tawatchai; Breitenstein, Matthew K.; Schousboe, John   Rheumatoid Arthritis: Preoperative Evaluation for Total Hip and Total Knee Replacement Surgery Goodman, Susan M.   Psoriasis and Psoriatic Arthropathy, Historical Aspects: Part I Benedek, Thomas G.   Granulomatosis With Polyangiitis Presenting as Henoch-Schönlein Purpura in Children Bui, Tuan; Chandrakasan, Shanmuganathan; Poulik, Janet; Fathalla, Basil M.   Palmar Fasciitis and Polyarthritis Syndrome in Pancreatic Carcinoma Veitch, David; Tsai, Ted; Joshua, Fredrick   A Case of Bilateral Hemarthrosis Due to Pseudoaneurysms in a Patient on Anticoagulation Therapy Son, Kyeong Min; Kim, Ja Kyung; Seo, Young Il; Kim, Hyun Ah   A Case of Isolated Aorta Occlusion Caused by Takayasu Arteritis Tan, Chun-Yu; Qin, Wei; Zhao, Yi; Yang, Yi; Huang, Zi-Xing; Liu, Y   British Medical Journal 25 May 2013 (Vol 346, Issue 7909)  Breast cancer detection and survival among women with cosmetic breast implants: systematic review and meta-analysis of observational studies Eric Lavigne, epidemiologist, Eric J Holowaty, adjunct professor, Sai Yi Pan, epidemiologist, Paul J Villeneuve, senior research scientist, Kenneth C Johnson, adjunct professor, Dean A Fergusson, senior scientist and director,Howard Morrison, director, Jacques Brisson, full professor   The gap in life expectancy from preventable physical illness in psychiatric patients in Western Australia: retrospective analysis of population based registers David Lawrence, research professor1, Kirsten J Hancock, senior analyst1, Stephen Kisely, professor   Completeness and diagnostic validity of recording acute myocardial infarction events in primary care, hospital care, disease registry, and national mortality records: cohort study Emily Herrett, research fellow, Anoop Dinesh Shah, clinical research fellow,Rachael Boggon, research statistician, Spiros Denaxas, senior research associate, Liam Smeeth, professor of clinical epidemiology and general practitioner, Tjeerd van Staa, professor of pharmacoepidemiology, Adam Timmis, professor of clinical cardiology, Harry Hemingway, professor of clinical epidemiology   Use of serum C reactive protein and procalcitonin concentrations in addition to symptoms and signs to predict pneumonia in patients presenting to primary care with acute cough: diagnostic study Saskia F van Vugt, general practitioner , Berna D L Broekhuizen, assistant professor, Christine Lammens, analyst, Nicolaas P A Zuithoff, assistant professor, Pim A de Jong, radiologist, Samuel Coenen, assistant professor,Margareta Ieven, professor, Chris C Butler, professor, Herman Goossens, professor, Paul Little, professor5, Theo J M Verheij, professor on behalf of the GRACE consortium   American Family Physician May 15, 2013, Vol. 87 N. 10 Approach to Acute Headache in Adults Barry L. Hainer ; Eric M. Matheson   Sick Sinus Syndrome: A Review Michael Semelka ; Jerome Gera ; Saif Usman   Ulcerative Colitis Stephen M. Adams ; Paul H. Bornemann

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