Colegio Mexicano de Ortopedia y Traumatología

Colegio Mexicano de Ortopedia y Traumatología
CMO en linea....

sábado, 30 de marzo de 2013

It is estimated that every day 25000 people sprain their ankle

                                                  http://www.smo.edu.mx/jornada2013/

http://www.webmd.com/fitness-exercise/ankle-injuries-causes-and-treatments


It is estimated that every day 25000 people sprain their ankle.

viernes, 29 de marzo de 2013

Prótesis de Tobillo Salto. Ankle prosthesis

                                                  http://www.smo.edu.mx/jornada2013/




Publicado el 25/03/2013
Intervención de una prótesis de tobillo Salto, en las Segundas Jornadas de Cirugía en directo en el Hospital San Juan de Dios de Córdoba.

La tasa de complicaciones de la artroscopia es mayor de lo pensado

                                                  http://www.smo.edu.mx/jornada2013/


http://www.intramed.net/contenidover.asp?contenidoID=79708
26 MAR 13 | Cirugía de cadera
La tasa de complicaciones de la artroscopia es mayor de lo pensado
Un tipo de cirugía de la cadera presenta más complicaciones de las que se pensaba.

Medlineplus
 
Mary Elizabeth Dallas

La tasa de complicaciones de la artroscopia, un procedimiento quirúrgico mínimamente invasivo para reparar el daño dentro de una articulación, es mayor de lo que se pensaba, halla un estudio reciente.

Los investigadores señalaron que los informes anteriores sobre las complicaciones no eran completos, y no incluían las nuevas técnicas quirúrgicas, como la reparación del lábrum de la cadera. Sugirieron que sus hallazgos podrían ayudar a los médicos a prevenir las complicaciones asociadas con la artroscopia de la cadera en el futuro.

El nuevo estudio analizó la información de casi 600 artroscopias de cadera que se llevaron a cabo en tres hospitales entre enero de 2011 y abril de 2012. Los pacientes, cuya edad promedio era de alrededor de 32 años, incluyó el mismo número de hombres y mujeres. Los investigadores tomaron en cuenta el diagnóstico individual, la información demográfica y el procedimiento de los pacientes.

"La tasa general de complicaciones tras la artroscopia de cadera fue del 7.2 por ciento, que es más alto de lo que la literatura había reportado antes, un 1.5 por ciento", señaló en un comunicado de prensa el autor líder del estudio, el Dr. Christopher Larson, del Instituto de Medicina Deportiva Ortopédica de Minnesota, en Minneapolis.

Las molestias sensoriales en la pierna fue la complicación más común, y ocurrió en casi el 23 por ciento de los casos. Los investigadores apuntaron que ese efecto no persistió más allá de los seis meses, excepto en cuatro casos.

No se observó una diferencia en las complicaciones según el sexo de los pacientes, ni entre los procedimientos realizados por primera vez en comparación con las revisiones.

"Esperamos que nuestra investigación ayude a proveer nueva información sobre las complicaciones de la cirugía, y cómo prevenirlas", planteó Larson.

Los hallazgos del estudio se presentaron el sábado en la reunión anual de la Sociedad Americana Ortopédica para la Medicina Deportiva (American Orthopaedic Society for Sports Medicine), en Chicago. Los datos y las conclusiones deben considerarse como preliminares hasta que se publiquen en una revista reseñada por profesionales.


FUENTE: American Orthopaedic Society for Sports Medicine

El cirujano Alejandro Badia participará en simposio sobre ortopedia

La artrosis y la osteoporosis pueden coexistir

                                                  http://www.smo.edu.mx/jornada2013/




Blog de la Condroprotección has posted a new item,
 'La artrosis y la osteoporosis pueden coexistir'

Como sabéis, en la actualidad existía la creencia de una posible “situación
de inmunidad” a sufrir osteoporosis por parte de los pacientes con artrosis;
esto se debe a que los pacientes con patología degenerativa articular tenían
mayor masa ósea que el resto de la población y por consecuencia menor
probabilidad de sufrir fracturas.

Sin embargo, empiezan [...]

You may view the latest post at
http://www.condroprotectores.es/la-artrosis-y-la-osteoporosis-pueden-coexistir/

Destacan servicio de Telemedicina del Issste

                                                  http://www.smo.edu.mx/jornada2013/




Destacan servicio de Telemedicina del Issste
En un recorrido realizado por el Hospital General “B” del Issste Presidente Gral. Lázaro Cárdenas, el Delegado Estatal Jorge Esteban Sandoval acompañado por los Subdelegados, tuvo la oportunidad de recibir una narrativa del Sistema de Telemedicina la cual a lo largo de 18 años de existencia, el sistema de Tele-salud del Issste, fue el pionero a nivel mundial en las instituciones públicas de salud, en el cual hasta la fecha se suman más de 17 mil 500 servicios de asistencia médica a distancia, al enlazar a 18 hospitales generales y regionales del Instituto en el país, agilizando la consulta de alta especialidad a favor de los pacientes, este sistema fue reconocido por la Organización Mundial de la Salud como el más productivo en el mundo.
http://www.frontenet.com/notas/20130326/destacan_servicio_de_telemedicina_del_issste

¿Dolor de rodilla?Meniscos y artroscopia

                                                  http://www.smo.edu.mx/jornada2013/





martes, 26 de marzo de 2013

¿Dolor de rodilla?Meniscos y artroscopia

La artroscopia de rodilla ha ganado éxito a lo largos de los años por los primeros actos que se realizaban mediante ella, las meniscectomías o resecciones de meniscos. Desde el año 2002 nadie se plantea operar un menisco mediante amplias incisiones en la rodilla como se hacía antiguamente.
La artroscopia precisa por parte del traumatólogo un largo período de aprendizaje para obtener buenos resultados. No exenta de riesgos, es una técnica que tu especialista evaluará con precisión y deberá explicarte el pronóstico de la misma. Siempre se debe explicar al paciente las expectativas a corto, medio y largo plazo....

A new era in sports science journals: the launch of BMC Sports Science, Medicine and Rehabilitation

                                                  http://www.smo.edu.mx/jornada2013/



http://www.stonehearthnewsletters.com/a-new-era-in-sports-science-journals-the-launch-of-bmc-sports-science-medicine-and-rehabilitation/exercise/?goback=%2Egde_3422483_member_227237575


A new era in sports science journals: the launch of BMC Sports Science, Medicine and Rehabilitation stonehearthnewsletters.com
Open access publisher BioMed Central is proud to announce the launch of BMC Sports Science, Medicine and Rehabilitation, another addition to the BMC-series portfolio. The journal’s scope includes all aspects of sports medicine...
http://www.stonehearthnewsletters.com/a-new-era-in-sports-science-journals-the-launch-of-bmc-sports-science-medicine-and-rehabilitation/exercise/?goback=.gde_3422483_member_227237575

The importance of considering 3 Dimensional Sports Rehabilitation with Achilles injuries. Opinión entre pares

                                                  http://www.smo.edu.mx/jornada2013/


Grupo cerrado. http://www.linkedin.com/groups/Sports-Medicine-Updates-3422483?trk=myg_ugrp_ovr

Sports Medicine Updates. Grupo cerrado. Opinión entre pares


Paul Newcombe

The importance of considering 3 Dimensional Sports Rehabilitation with Achilles injuries

3D Sports Rehabilitation: The Achilles

Background of Achilles injuries in sports

Achilles injuries are one of the most common injuries to the lower leg. The Achilles injury is most commonly caused when an athlete is running, with the foot in contact with the ground. This often occurs during a dynamic change in direction, most commonly during the pushing off phase of the leg in contact with the ground upon the change of direction. This causes damage in the tissue ranging from a mild strain to a complete rupture. Although these injuries are often caught early enough and rehabilitated, often these are re-injured within a relatively short period, and often result in the once acute injury becoming a more chronic condition of Achilles tendinopathy. Athletes often re-injure the Achilles upon returning to running activities with change of direction work, and often when they return to full participation in their sport.

Alfredson et al (1998) state that in order to rehabilitate and Achilles tendinopathy injury, a protocol of eccentric loading of the Achilles tendon is to be followed. This consists of eccentric loading of the Achilles whilst lowering under control the return motion from a heel raise exercise, often from a step, working against gravity initially. This is repeated for 3 sets of 15 reps, twice a day, 7 days per week for 12 weeks, and studies have suggested that this has a positive outcome on Achilles injuries. There are however, occasions when this protocol has been followed, and there still follows further injuries to the Achilles, accompanied by a return of the original symptoms.

The ankle joint does not operate on one plane around a single axis. The ankle joint allows movement on all three planes around all three axis. As well as movements of plantar flexion and dorsi flexion on the sagital plane around the frontal axis, there is also lateral movement of the ankle joint along the frontal plane and sagital axis, and rotational movement on the horizontal a plane around the vertical axis. During the stance phase of gait, rather that the foot just moving into plantar and dorsi flexion on the sagital plane around the frontal axis, the foot also moves from supination into pronation, which in itself provides an element of rotation and lateral flexion. This places greater tension upon the Achilles that can be achieved when we follow just the Alfredson protocol of heel raise eccentric loading.

Importance of 3 dimensional approach to rehabilitation

In order to ensure that the Achilles is in a less vulnerable position when an athlete returns to running and change of direction work, there needs to be some element of rehabilitation that involves the other actions of the muscles that attach to the Achilles. This would ensure that we cover the other two planes of movement and ensure that these are sufficiently strengthened in order to reduce the chances of re-injury once we add in the functional movement of pronation and supination at the foot, which puts the Achilles at maximum stress. It seems unthinkable that we should follow Alfredsons procedures, without considering all 3 planes of movement that the Achilles is involved with around the foot/ankle joint. This can be easily achieved in the early stages of rehabilitation with the addition of some simple exercises in a two legged standing position, progressing to single legged, to ensure that the Achilles can assist in the control of the foot into pronation and supination, progressively moving into a dorsiflexed position which will progressively load the Achilles in a position that it will be in upon the commencement of running gait. This can all be achieved prior to commencing the more functional dynamic movements, reducing the risk of injury, and progression into a chronic state with the Achilles.

4th Annual PRP & Regenerative Medicine Symposium.

                                                   http://www.smo.edu.mx/jornada2013/




http://www.prpseminar.com/4th-annual-prp-regenerative-medicine-symposium/?goback=.gde_4464752_member_227223068

Platelet Rich Plasma: Understanding the Variables by Kenneth R. Mautner, MD, Emory Sports Medicine Center, Atlanta, GA Quantification and Standardization of Autologous Biologics – a Logical Progression by David C. Karli, MD,...

The Orthbiologic Institute TOBI Faculty present new research that shows Platelet Rich Plasma PRP effective for Knee Osteoarthritis with 2 year follow up
TOBI Faculty & colleagues Alberto Gobbi MD, Georgios Karnatzikos MD from Milan, Italy presented new research at the world’s largest gathering of Orthopaedic Surgeons in Chicago, Illinois last week, the AAOS (American Academy of Orthopaedic Surgery).

This study shows PRP Platelet Rich Plasma effective for Knee Osteoarthritis with 2 year follow up.

PRP intra-articular knee injections are effective both in operated and non-operated arthritic knees and can act as a preventive agent of Osteoarthritis, by diminishing pain and improving symptoms and quality of life.

Patients who repeated PRP treatment preserved a better clinical outcome, indicating that PRP injections can provide a better outcome when repeated.

This study builds on our pilot clinical trial for knee arthritis with PRP that showed significant improvement at 1 year follow up. More and more studies are emerging that demonstrate the cost effectiveness and therapeutic benefit of PRP for arthritis.

View abstract: http://www.abstractsonline.com/plan/ViewAbstract.aspx?mID=2984&sKey=b41dc57e-bb15-4560-969c-68c2bfda02c3&cKey=fa0e8f0a-3048-4e0c-9186-7e42bbbc86fb&mKey=%7B342D5FB6-3E41-46BB-82B4-861286ECFB41%7D

Large Randomized Trial Confirms Value of Platelet Rich Plasma for Tennis Elbow Patients

                                                   http://www.smo.edu.mx/jornada2013/



http://www.bloodcure.com/
Excelente!!!!
THURSDAY, MARCH 21, 2013

Large Randomized Trial Confirms Value of Platelet Rich Plasma for Tennis Elbow Patients
84% of patients with chronic tennis elbow who had failed other non-operative treatment...Ver más

jueves, 28 de marzo de 2013

A Glimpse into the Future of Orthopedic Biomaterials

                                                   http://www.smo.edu.mx/jornada2013/


http://www.qmed.com/mpmn/medtechpulse/glimpse-future-orthopedic-biomaterials?cid=nl_mpmn_medtech_pulse&utm_source=Qmed&utm_medium=Twitter&utm_campaign=Alex%20Social

A Glimpse into the Future of Orthopedic Biomaterials

In this interview with MPMN, William Fuller, director of business development at DSM Biomedical (Berkeley, CA) paints a picture of biomaterials' future in procedures such as total hip or knee replacement. Among the topics discussed here are hindered amine light stabilizer (HALS), which can be used in total hip, knee, shoulder, and ankle implants to stabilize ultra-high molecular weight polyethylene (UHMWPE). Fuller also touches on biomaterials that could be used to replace damaged cartilage and provides an overview of how future biomaterial breakthroughs will drive innovation in orthopedics........

X-Rays Spring Colors

                                                  http://www.smo.edu.mx/jornada2013/



http://physicsbuzz.physicscentral.com/2013/03/x-rays-spring-colors.html

Thursday, March 28, 2013



X-Rays Spring Colors

"I have seen my death!" proclaimed Anna Roetgen in December of 1895. Anna Roetgen saw through skin, muscle and blood to the dark and askew shape of the bones in her hand. Her husband, Wilhelm Roetgen, had uncovered a mysterious kind of ray.
print of one of the first X-rays by Wilhelm Röntgen (1845–1923)
of the left hand of his wife Anna Bertha Ludwig. 

He called it the X-ray.


This week, researchers at the Stanford Linear Accelerator announced that they have created an x-ray beam with two slightly different colors. The research was published in the Physical Review Letters on March 25, 2013.

Depending on their electronic structure, atoms and molecules can interact with light differently. Tuning the color of the x-rays will allow researchers to pick out specific atomic and molecular dynamics like how bonds break and rearrange in chemical reactions.

X-rays are a form ofelectromagnetic radiation with a wavelength shorter than UV and visible light but longer than gamma rays. X-ray photons are emitted when an atom is hit with such energy that an electron in an inner orbital excites, or when electrons, accelerated to very high speeds, slam into a metal target. The wavelength of x-rays is so small that x-rays can penetrate deep into materials without scattering or losing energy. Probing the inside of dense matter,  x-rays have become a touchstone for science from medical diagnosis to materials research.

Now, scientists are bringing x-rays to the next level. For the past century, most of the energy required to get electrons to produce x-rays was lost as heat. Moreover, techniques for making x-rays resulted in the electrons producing many wavelengths within the x-ray spectrum. With the goal of studying atoms and molecules in motion, scientists want to use x-rays that are all the same color, phase, and direction. These are called coherent x-rays.

There are only a handful of places in the world where it's possible to find coherent x-rays. One is the Stanford Linear Accelerator Linac Coherent Light Source. At the SLAC Linac, scientists send electrons down a two-mile-long shoot where they are jostled by strong magnetic fields to produce x-rays. In the research published this week, by offsetting two magnetic fields, the team was able to produce pulses of coherent x-rays at slightly different wavelengths.  Using bursts of x-rays, like a strobe light, the researchers were able to take what are effectively stop-motion photos of molecules in motion.

While new methods of controlling x-ray generation will push the bounds of chemical and materials science, accelerators like SLAC offer scientists limited time to use its x-ray laser beams. To address this, last year a research group at CU Boulder and JILA demonstrated a table-top opportunity to study nature at the ultrafast and ultrasmall scale. We should all look forward to the treasure chest of new science within reach now that x-ray laser sources become more precise and available!


Neurological impairment score in lumbar spinal stenosis

                                                   http://www.smo.edu.mx/jornada2013/


http://www.mdlinx.com/orthopedics/news-article.cfm/4513321/spinal-stenosis


Neurological impairment score in lumbar spinal stenosis 
European Spine Journal, 03/19/2013  Evidence Based Medicine

Adamova BM et al. – Authors developed a scoring system [neurological impairment score in lumbar spinal stenosis (NIS–LSS)] for the assessment of neurological impairment in the lower limbs of patients with LSS, then performed a validation study to facilitate its implementation in the routine clinical evaluation of patients with LSS. The NIS–LSS is a simple and valid measure of neurological impairment in the lower limbs of patients with LSS (without comorbidity), discriminating them from healthy controls to a high degree of sensitivity and specificity and correlating closely with the degree of disability. It extends our ability to quantify neurological status and to follow changes arising out of the natural course of the disease or the effects of treatment.
► Link to PubMed, Publisher, See related articles and more ..


Read more: http://www.mdlinx.com/orthopedics/news-article.cfm/4513321/spinal-stenosis#ixzz2OtqniArT

Email therapy for your patients...

                                                  http://www.smo.edu.mx/jornada2013/


http://online.wsj.com/article/SB10001424127887324373204578376863506224702.html?goback=%2Egde_1170817_member_226960447


Key Concepts for Clinical & Quality of Care Research in Spine Surgery: Q&A With Dr. Artem Vaynman of Neurological Surgery

viernes, 22 de marzo de 2013

FACTORES DE CRECIMIENTO Y ROTURA DE TENDON DE AQUILES

                                                  http://www.smo.edu.mx/jornada2013/


http://cirugiadelpie.blogspot.mx/2013/03/factores-de-crecimiento-y-rotura-de.html?utm_source=feedburner&utm_medium=email&utm_campaign=Feed:+CirugiaDelPie+(CIRUGIA+DEL+PIE.+Traumat%C3%B3logo+Dr.+Jorge+de+las+Heras)&utm_content=Yahoo!+Mail


CIRUGIA DEL PIE. Traumatólogo Dr. Jorge de las Heras



Posted: 22 Mar 2013 12:53 PM PDT
Un estudio sobre rotura del tendón de Aquiles ha sido recientemente presentado en el congreso de la American Academy of Orthopedic Surgeons (AAOS) de este año (Sociedad más importante de Traumatólogos de Estados Unidos)

Llegan a la conclusión de que la recuperación tras una rotura de tendón de Aquiles, sea tratada de forma ortopédica (sin cirugía) como con cirugía percutánea (mínima incisión) se ve acelerada mostrando una regeneración más precoz cuando se complementa con la inyección de lo que se denomina factores de crecimiento, de tal forma que los pacientes pueden reincorporarse antes a sus actividades de trabajo o deportivas.

Se trata de una prueba más de que los factores de crecimiento son útiles en muchas dolencias del sistema musculoesquelético, como ya se ha demostrado en otros estudios similares en otras localizaciones.

Novedades de las revistas más importantes en Condroprotección




http://www.condroproteccion.es/

A continuación le mostramos las novedades de las revistas más importantes en Condroprotección
 
 
 Clasificación semicuantitativa de la patología articular mediante IRM en artrosis 
 Nat Rev Rheumatol. 2013 Jan15. doi: 10.1038/nrrheum.2012.223 [publicación electrónica previa a la publicación impresa] 
 Regulación por disminución de la muerte celular programada 5 mediante el factor de crecimiento tipo insulina 1 en condrocitos artrósicos 
 Int Orthop. 2013 Jan 16 [publicación electrónica previa a la publicación impresa] 






Arthritis & Rheumatism
Volume 65, Issue 3, March 2013
Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: Twelve-month data from a twenty-four-month phase III randomized radiographic study
Désirée van der Heijde, Yoshiya Tanaka, Roy Fleischmann, Edward Keystone, Joel Kremer, Cristiano Zerbini, Mario H. Cardiel, Stanley Cohen, Peter Nash, Yeong-Wook Song, Dana Tegzová, Bradley T. Wyman, David Gruben, Birgitta Benda, Gene Wallenstein, Sriram Krishnaswami, Samuel H. Zwillich, John D. Bradley and Carol A. Connell, and the ORAL Scan Investigators
 
Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls
Katherine P. Liao, Fina Kurreeman, Gang Li, Grant Duclos, Shawn Murphy, Raul Guzman, Tianxi Cai, Namrata Gupta, Vivian Gainer, Peter Schur, Jing Cui, Joshua C. Denny, Peter Szolovits, Susanne Churchill, Isaac Kohane, Elizabeth W. Karlson and Robert M. Plenge
 
A genetic variant in granzyme B is associated with progression of joint destruction in rheumatoid arthritis
R. Knevel, A. Krabben, A. G. Wilson, E. Brouwer, M. K. Leijsma, E. Lindqvist, D. P. C. de Rooy, N. A. Daha, M. P. M. van der Linden, S. Tsonaka, A. Zhernakova, H.-J. Westra, L. Franke, J. J. Houwing-Duistermaat, R. E. M. Toes, T. W. J. Huizinga, T. Saxne and A. H. M. van der Helm-van Mil
 
Association of an activity-enhancing variant of IRAK1 and an MECP2-IRAK1 haplotype with increased susceptibility to rheumatoid arthritis
Tae-Un Han, Soo-Kyung Cho, Taehyeung Kim, Young Bin Joo, Sang-Cheol Bae and Changwon Kang
 
Abatacept (CTLA-4IG) treatment reduces the migratory capacity of monocytes in patients with rheumatoid arthritis
M. Bonelli, E. Ferner, L. Göschl, S. Blüml, A. Hladik, T. Karonitsch, H. P. Kiener, R. Byrne, B. Niederreiter, C. W. Steiner, E. Rath, M. Bergmann, J. S. Smolen and C. Scheinecker
 
Tumor necrosis factor-inhibiting therapy preferentially targets bone destruction but not synovial inflammation in a tumor necrosis factor-driven model of rheumatoid arthritis†
Nikolaus B. Binder, Antonia Puchner, Birgit Niederreiter, Silvia Hayer, Harald Leiss, Stephan Blüml, Roman Kreindl, Josef S. Smolen and Kurt Redlich
 
Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling
Song Ling, Erika N. Cline, Timothy S. Haug, David A. Fox and Joseph Holoshitz
 
Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127low regulatory T cells
Gina J. Walter, Hayley G. Evans, Bina Menon, Nicola J. Gullick, Bruce W. Kirkham, Andrew P. Cope, Frédéric Geissmann and Leonie S. Taams
 
Simvastatin inhibits cysteine-rich protein 61 expression in rheumatoid arthritis synovial fibroblasts through the regulation of sirtuin-1/FoxO3a signaling
Sang-Heng Kok, Li-Deh Lin, Kuo-Liang Hou, Chi-Yuan Hong, Cheng-Chi Chang, Michael Hsiao, Jyh-Horng Wang, Eddie Hsiang-Hua Lai and Sze-Kwan Lin
 
Type II collagen-specific antibodies induce cartilage damage in mice independent of inflammation
Allyson M. Croxford, Senga Whittingham, Donald McNaughton, Kutty Selva Nandakumar, Rikard Holmdahl and Merrill J. Rowley
 
Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice
John S. Lewis Jr., Bridgette D. Furman, Evan Zeitler, Janet L. Huebner, Virginia B. Kraus, Farshid Guilak and Steven A. Olson
 
Therapeutic efficacy of Tyro3, Axl, and Mer tyrosine kinase agonists in collagen-induced arthritis
B. T. van den Brand, S. Abdollahi-Roodsaz, E. A. Vermeij, M. B. Bennink, O. J. Arntz, C. V. Rothlin, W. B. van den Berg and F. A. J. van de Loo
 
Host-derived CD4+ T cells attenuate stem cell-mediated transfer of autoimmune arthritis in lethally irradiated C57BL/6.g7 mice
Narendiran Rajasekaran, Nan Wang, Phi Truong, Cornelia Rinderknecht, Claudia Macaubas, Georg F. Beilhack, Judith A. Shizuru and Elizabeth D. Mellins
 
Bone parameters across different types of hip osteoarthritis and their relationship to osteoporotic fracture risk
Martha C. Castaño-Betancourt, Fernando Rivadeneira, Sita Bierma-Zeinstra, Hanneke J. M. Kerkhof, Albert Hofman, Andre G. Uitterlinden and Joyce B. J. van Meurs
 
Effects of a modified shoe on knee load in people with and those without knee osteoarthritis
Kim L. Bennell, Crystal O. Kean, Tim V. Wrigley and Rana S. Hinman
 
Matrix-assisted laser desorption ionization-imaging mass spectrometry: A new methodology to study human osteoarthritic cartilage
Berta Cillero-Pastor, Gert B. Eijkel, Andras Kiss, Francisco J. Blanco and Ron M. A. Heeren
 
Sclerostin is expressed in articular cartilage but loss or inhibition does not affect cartilage remodeling during aging or following mechanical injury†
Martine Roudier, Xiaodong Li, Qing-Tian Niu, Efrain Pacheco, James K. Pretorius, Kevin Graham, Bo-Rin P. Yoon, Jianhua Gong, Kelly Warmington, Hua Z. Ke, Roy A. Black, Joanne Hulme and Philip Babij
 
Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes
María C. de Andrés, Kei Imagawa, Ko Hashimoto, Antonio Gonzalez, Helmtrud I. Roach, Mary B. Goldring and Richard O. C. Oreffo
 
Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice
Jessica Bertrand, Richard Stange, Heriburg Hidding, Frank Echtermeyer, Giovanna Nalesso, Lars Godmann, Melanie Timmen, Peter Bruckner, Francesco Dell’Accio, Michael J. Raschke, Thomas Pap and Rita Dreier
 
Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004†
Candace H. Feldman, Linda T. Hiraki, Jun Liu, Michael A. Fischer, Daniel H. Solomon, Graciela S. Alarcón, Wolfgang C. Winkelmayer and Karen H. Costenbader
 
Increased expression of a short splice variant of CTLA-4 exacerbates lupus in MRL/lpr mice
Kunihiro Ichinose, Zheng Zhang, Tomohiro Koga, Yuang-Taung Juang, Katalin Kis-Tóth, Arlene H. Sharpe, Vijay Kuchroo, José C. Crispín and George C. Tsokos
 
CD22 ligation inhibits downstream B cell receptor signaling and Ca2+ flux upon activation
N. Sieger, S. J. Fleischer, H. E. Mei, K. Reiter, A. Shock, G. R. Burmester, C. Daridon and T. Dörner
 
Inducible expression of kallikrein in renal tubular cells protects mice against spontaneous lupus nephritis
Xinli Shao, Ru Yang Mei Yan, Yajuan Li, Yong Du, Indu Raman, Bo Zhang, Ward Wakeland, Peter Igarashi, Chandra Mohan and Quan-Zhen Li
 
Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model
Agatha Stegemann, Anca Sindrilaru, Beate Eckes, Adriana del Rey, Alexander Heinick, Jan S. Schulte, Frank U. Müller, Sergei A. Grando, Bernd L. Fiebich, Karin Scharffetter-Kochanek, Thomas A. Luger and Markus Böhm
 
Evaluation of intravenous immunoglobulin resistance and coronary artery lesions in relation to Th1/Th2 cytokine profiles in patients with Kawasaki disease
Yujia Wang, Wei Wang, Fangqi Gong, Songling Fu, Qing Zhang, Jian Hu, Yanqi Qi, Chunhong Xie and Yiying Zhang
 
Neutrophil cannibalism triggers transforming growth factor β1 production and self regulation of neutrophil inflammatory function in monosodium urate monohydrate crystal-induced inflammation in mice
Stefanie Steiger and Jacquie L. Harper
 
Hearing loss in Muckle-Wells syndrome
Jasmin B. Kuemmerle-Deschner, Assen Koitschev, Katharina Ummenhofer, Sandra Hansmann, Stefan K. Plontke, Christiane Koitschev, Ina Koetter, Eva Angermair and Susanne M. Benseler
 
Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1
Jianru Wang, Ye Tian, Kate L. E. Phillips, Neil Chiverton, Gail Haddock, Rowena A. Bunning, Alison K. Cross, Irving M. Shapiro, Christine L. Le Maitre and Makarand V. Risbud
 





The Journal of Rheumatology
March 2013; 40 (3)
Screening Citrullinated Proteins in Synovial Tissues of Rheumatoid Arthritis Using 2-dimensional Western Blotting
XIAOTIAN CHANG, YAN ZHAO, YUEJIAN WANG, YU CHEN, and XINFENG YAN
 
The SMILE Study - Safety of Methotrexate in Combination with Leflunomide in Rheumatoid Arthritis
PAUL BIRD, HEDLEY GRIFFITHS, KATHLEEN TYMMS, DAVE NICHOLLS,LYNDEN ROBERTS, MARK ARNOLD, SIMON BURNET, JULIEN de JAGER, JAMES SCOTT, JANE ZOCHLING, and GEOFF LITTLEJOHN
 
The Relationship Between Cognitive Function and Physical Function in Rheumatoid Arthritis
SO YOUNG SHIN, LAURA JULIAN, and PATRICIA KATZ
 
Factors Influencing Concordance Between Clinical and Ultrasound Findings in Rheumatoid Arthritis
MARION Le BOEDEC, SANDRINE JOUSSE-JOULIN, JEAN-FRANÇOIS FERLET,THIERRY MARHADOUR, GÉRARD CHALES, LAURENT GRANGE, CÉCILE HACQUARD-BOUDER, DAMIEN LOEUILLE, JÉRÉMIE SELLAM, JEAN-DAVID ALBERT, JACQUES BENTIN, ISABELLE CHARY-VALCKENAERE, MARIA-ANTONIETTA D'AGOSTINO, FABIEN ETCHEPARE, PHILIPPE GAUDIN,CHRISTOPHE HUDRY, MAXIME DOUGADOS, and ALAIN SARAUX
 
Three-dimensional Volumetric Ultrasound: A Valid Method for Blinded Assessment of Response to Therapy in Rheumatoid Arthritis
ESPERANZA NAREDO, CARLOS ACEBES, ELIA BRITO, JUAN JOSÉ de AGUSTÍN,EUGENIO de MIGUEL, LUCÍA MAYORDOMO, INGRID MÖLLER, CARMEN MORAGUES, EDUARDO REJÓN, ANA RODRIGUEZ, JACQUELINE USON, JESÚS GARRIDO, DAVID MARTÍNEZ-HERNÁNDEZ, and the Ultrasound School of the Spanish Society of Rheumatology
 
Symptoms Related to Tumor Necrosis Factor Receptor 1-associated Periodic Syndrome, Multiple Sclerosis, and Severe Rheumatoid Arthritis in Patients Carrying the TNF Receptor Superfamily 1A D12E/p.Asp41Glu Mutation
JOACHIM HAVLA, PETER LOHSE, LISA ANN GERDES, REINHARD HOHLFELD,and TANIA KÜMPFEL
 
The Effect of Vitamin D Supplementation on Inflammatory and Hemostatic Markers and Disease Activity in Patients with Systemic Lupus Erythematosus: A Randomized Placebo-controlled Trial
ANNA ABOU-RAYA, SUZAN ABOU-RAYA, and MADIHAH HELMII
 
Shrinking Lung Syndrome as a Manifestation of Pleuritis: A New Model Based on Pulmonary Physiological Studies
LAUREN A. HENDERSON, STEPHEN H. LORING, RITU R. GILL, KATHERINE P. LIAO, RUMEY ISHIZAWAR, SUSAN KIM, ROBIN PERLMUTTER-GOLDENSON,DEBORAH ROTHMAN, MARY BETH F. SON, MATTHEW L. STOLL, LAWRENCE S. ZEMEL, CHRISTY SANDBORG, PAUL F. DELLARIPA, and PETER A. NIGROVIC
 
Utility of Antiphosphatidylserine/Prothrombin and IgA Antiphospholipid Assays in Systemic Lupus Erythematosus
EHTISHAM AKHTER, ZAKERA SHUMS, GARY L. NORMAN, WALTER BINDER,HONG FANG, and MICHELLE PETRI
 
Limitations in Screening Instruments for Psoriatic Arthritis: A Comparison of Instruments in Patients with Psoriasis
JESSICA A. WALSH, KRISTINA CALLIS DUFFIN, GERALD G. KRUEGER, andDANIEL O. CLEGG
 
BAFF Expression Correlates with Idiopathic Inflammatory Myopathy Disease Activity Measures and Autoantibodies
CONSUELO M. LÓPEZ De PADILLA, KELLY T. McNALLAN, CYNTHIA S. CROWSON, HATICE BILGIC, RICHARD J. BRAM, MOLLY S. HEIN, STEVEN R. YTTERBERG, SHREYASEE AMIN, ERIK J. PETERSON, EMILY C. BAECHLER, andANN M. REED
 
Homocysteine Levels in Takayasu Arteritis - A Risk Factor for Arterial Ischemic Events
ALEXANDRE WAGNER SILVA DE SOUZA, CARLA SERRANO DE LIMA, ANA CECILIA DINIZ OLIVEIRA, LUIZ SAMUEL GOMES MACHADO, FREDERICO AUGUSTO GURGEL PINHEIRO, SONIA HIX, and VANIA D'ALMEIDA
 
A New Approach to Prevention of Knee Osteoarthritis: Reducing Medial Load in the Contralateral Knee
RICHARD K. JONES, GRAHAM J. CHAPMAN, ANDREW H. FINDLOW, LAURA FORSYTHE, MATTHEW J. PARKES, JAWAD SULTAN, and DAVID T. FELSON
 
Association of Guanosine Triphosphate Cyclohydrolase 1 Gene Polymorphisms with Fibromyalgia Syndrome in a Korean Population
SEONG-KYU KIM, SEONG-HO KIM, SEONG-SU NAH, JI HYUN LEE, SEUNG-JAE HONG, HYUN-SOOK KIM, HYE-SOON LEE, HYOUN AH KIM, CHUNG-IL JOUNG, JISUK BAE, JUNG-YOON CHOE, and SHIN-SEOK LEE
 
A Medicolegal Analysis of Worker Appeals for Fibromyalgia as a Compensable Condition Following Workplace Soft-tissue Injury
MARY-ANN FITZCHARLES, PETER A. STE-MARIE, and YORAM SHIR
 
Patients with Very Early-onset Systemic Juvenile Idiopathic Arthritis Exhibit More Inflammatory Features and a Worse Outcome
RICARDO A.G. RUSSO and MARÍA M. KATSICAS
 





Osteoarthritis and Cartilage
Volume 21, Issue 3, Pages 405-524 (March 2013)
The progression of end-stage osteoarthritis: analysis of data from the Australian and Norwegian joint replacement registries using a multi-state model
M.H. Gillam, S.A. Lie, A. Salter, O. Furnes, S.E. Graves, L.I. Havelin, P. Ryan
 
Peripatellar synovitis: comparison between non-contrast-enhanced and contrast-enhanced MRI and association with pain. The MOST study
M.D. Crema, D.T. Felson, F.W. Roemer, J. Niu, M.D. Marra, Y. Zhang, J.A. Lynch, G.Y. El-Khoury, C.E. Lewis, A. Guermazi
 
Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing - data from the Osteoarthritis Initiative
K. Bloecker, A. Guermazi, W. Wirth, O. Benichou, C.K. Kwoh, D.J. Hunter, M. Englund, H. Resch, F. Eckstein, for the OAI investigators
 
Three-dimensional turbo spin-echo magnetic resonance imaging (MRI) and semiquantitative assessment of knee osteoarthritis: comparison with two-dimensional routine MRI
M.D. Crema, M.H. Nogueira-Barbosa, F.W. Roemer, M.D. Marra, J. Niu, F.A. Chagas-Neto, E. Gregio-Junior, A. Guermazi
 
In vivo comparison of delayed gadolinium-enhanced MRI of cartilage and delayed quantitative CT arthrography in imaging of articular cartilage
J. Hirvasniemi, K.A.M. Kulmala, E. Lammentausta, R. Ojala, P. Lehenkari, A. Kamel, J.S. Jurvelin, J. Töyräs, M.T. Nieminen, S. Saarakkala
 
Statistical shape modeling of proximal femoral shape deformities in Legg-Calvé-Perthes disease and slipped capital femoral epiphysis
E.F. Chan, C.L. Farnsworth, J.A. Koziol, H.S. Hosalkar, R.L. Sah
 
Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees
C.-H. Chou, C.-H. Lee, L.-S. Lu, I.-W. Song, H.-P. Chuang, S.-Y. Kuo, J.-Y. Wu, Y.-T. Chen, V.B. Kraus, C.-C. Wu, M.T.M. Lee
 
Cluster analysis of infrared spectra can differentiate intact and repaired articular cartilage
Y. Kobrina, L. Rieppo, S. Saarakkala, H.J. Pulkkinen, V. Tiitu, P. Valonen, I. Kiviranta, J.S. Jurvelin, H. Isaksson
 
SIRT1, a class III histone deacetylase, regulates TNF-α-induced inflammation in human chondrocytes
M.-H. Moon, J.-K. Jeong, Y.-J. Lee, J.-W. Seol, C.J. Jackson, S.-Y. Park
 
Repair of osteochondral defects with recombinant human type II collagen gel and autologous chondrocytes in rabbit
H.J. Pulkkinen, V. Tiitu, P. Valonen, J.S. Jurvelin, L. Rieppo, J. Töyräs, T.S. Silvast, M.J. Lammi, I. Kiviranta
 
Injection of vascular endothelial growth factor into knee joints induces osteoarthritis in mice
A. Ludin, J.J. Sela, A. Schroeder, Y. Samuni, D.W. Nitzan, G. Amir
 
Molecular weight characterization of PRG4 proteins using multi-angle laser light scattering (MALLS)
B.L. Steele, M.C. Alvarez-Veronesi, T.A. Schmidt
 
Cell deformation behavior in mechanically loaded rabbit articular cartilage 4 weeks after anterior cruciate ligament transection
S.M. Turunen, S.-K. Han, W. Herzog, R.K. Korhonen
 
Deiodinase 2 upregulation demonstrated in osteoarthritis patients cartilage causes cartilage destruction in tissue-specific transgenic rats
H. Nagase, Y. Nagasawa, Y. Tachida, S. Sakakibara, J. Okutsu, N. Suematsu, S. Arita, K. Shimada
 





Journal of the American Academy of Orthopaedic Surgeons
March 2013; 21 (3) 
Acetabular Bone Loss in Revision Total Hip Arthroplasty: Evaluation and Management
Neil P. Sheth, Charles L. Nelson, Bryan D. Springer, Thomas K. Fehring,and Wayne G. Paprosky
 
Total Wrist Arthroplasty
Arnold-Peter C. Weiss, Robin N. Kamal, and Paul Shultz
 
Management of Fractures of the Proximal Ulna
Dominique M. Rouleau, Emilie Sandman, Roger van Riet,and Leesa M. Galatz
 
Obesity and Osteoarthritis: More Than Just Wear and Tear
Ryan C. Koonce and Jonathan T. Bravman
 
The Pediatric Polytrauma Patient: Current Concepts
Nirav K. Pandya, Vidyadhar V. Upasani, and Vedant A. Kulkarni
 
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
William Watters III, Michael P. Rethman, Nicholas Buck Hanson, Elliot Abt,Paul A. Anderson, Karen C. Carroll, Harry C. Futrell, Kevin Garvin,Stephen O. Glenn, John Hellstein, Angela Hewlett, David Kolessar,Calin Moucha, Richard J. O'Donnell, John E. O'Toole, Douglas R. Osmon,Richard Parker Evans, Anthony Rinella, Mark J. Steinberg,Michael Goldberg, Helen Ristic, Kevin Boyer, Patrick Sluka,William Robert Martin III, Deborah S. Cummins, Sharon Song,Anne Woznica, and Leeaht Gross
 





British Medical Journal
09 March 2013 (Vol 346, Issue 7898) 
Comparison of treatment effect sizes associated with surrogate and final patient relevant outcomes in randomised controlled trials: meta-epidemiological study
Oriana Ciani, PhD candidate, Marc Buyse, chairman, Ruth Garside, senior lecturer, Toby Pavey, research fellow, Ken Stein, professor, Jonathan A C Sterne, professor, Rod S Taylor, professor
 
Promotion of physical activity and fitness in sedentary patients with Parkinson's disease: randomised controlled trial
Marlies van Nimwegen, physiotherapist and research scientist1, Arlène D Speelman, physiotherapist and research scientist1, Sebastiaan Overeem, research scientist2, Bart P van de Warrenburg, medical doctor2, Katrijn Smulders, research scientist23, Manon L Dontje, research scientist45, George F Borm, professor in biostatistics6, Frank J G Backx, professor in clinical sports medicine7, Bastiaan R Bloem, professor in neurology2, Marten Munneke, physiotherapist and associate professor in health care innovation18 on behalf of the ParkFit Study Group
 
Mental disorders and vulnerability to homicidal death: Swedish nationwide cohort study
Casey Crump, clinical assistant professor, Kristina Sundquist, professor, Marilyn A Winkleby, professor, Jan Sundquist, professor and director
 
Income inequality and 30 day outcomes after acute myocardial infarction, heart failure, and pneumonia: retrospective cohort study
Peter K Lindenauer, associate professor of medicine, Tara Lagu, assistant professor of medicine, Michael B Rothberg, associate professor of medicine, Jill Avrunin, statistician, Penelope S Pekow, senior statistician,Yongfei Wang, lecturer in medicine, senior statistician, Harlan M Krumholz, Harold J Hines Jr professor of medicine
 





American Family Physician
March 1, 2013, Vol. 87 N. 5
Reducing the Risk of Adverse Drug Events in Older Adults
Richard W. Pretorius ; Gordana Gataric ; Steven K. Swedlund ; John R. Miller
 
Diabetic Ketoacidosis: Evaluation and Treatment
Dyanne P. Westerberg
 
Identification and Treatment of Amblyopia
Yasmin S. Bradfield
 





Physical Therapy
March 2013, Volume 93, Issue 3 
Many Randomized Trials of Physical Therapy Interventions Are Not Adequately Registered: A Survey of 200 Published Trials
Rafael Zambelli Pinto, Mark R. Elkins, Anne M. Moseley,Catherine Sherrington, Robert D. Herbert, Christopher G. Maher,Paulo H. Ferreira, and Manuela L. Ferreira
 
Efficacy of the Addition of Modified Pilates Exercises to a Minimal Intervention in Patients With Chronic Low Back Pain: A Randomized Controlled Trial
Gisela C. Miyamoto, Leonardo Oliveira Pena Costa, Thalissa Galvanin,and Cristina Maria Nunes Cabral
 
The STarT Back Screening Tool and Individual Psychological Measures: Evaluation of Prognostic Capabilities for Low Back Pain Clinical Outcomes in Outpatient Physical Therapy Settings
Jason M. Beneciuk, Mark D. Bishop, Julie M. Fritz, Michael E. Robinson,Nabih R. Asal, Anne N. Nisenzon, and Steven Z. George
 
People With Stroke Who Fail an Obstacle Crossing Task Have a Higher Incidence of Falls and Utilize Different Gait Patterns Compared With People Who Pass the Task
Catherine M. Said, Mary P. Galea, and Noel Lythgo
 
What Characterizes People Who Have an Unclear Classification Using a Treatment-Based Classification Algorithm for Low Back Pain? A Cross-Sectional Study
Tasha R. Stanton, Mark J. Hancock, Adri T. Apeldoorn, Benedict M. Wand,and Julie M. Fritz
 
Ultrasound Imaging Evaluation of Abdominal Muscles After Breast Reconstruction With a Unilateral Pedicled Transverse Rectus Abdominis Myocutaneous Flap
Lih-Jiun Liaw, Sin-Daw Lin, Lan-Yuen Guo, Yi-You Hou, Ming-Feng Hou,and Ar-Tyan Hsu
 
The First Two Years of Practice: A Longitudinal Perspective on the Learning and Professional Development of Promising Novice Physical Therapists
Lorna M. Hayward, Lisa L. Black, Elizabeth Mostrom, Gail M. Jensen,Pamela D. Ritzline, and Jan Perkins
 
Physical Activity in Students of the Medical University of Silesia in Poland
Magdalena Dąbrowska-Galas, Ryszard Plinta, Jolanta Dąbrowska,and Violetta Skrzypulec-Plinta
 
Reliability and Responsiveness of the Gross Motor Function Measure-88 in Children With Cerebral Palsy
Jooyeon Ko and MinYoung Kim
 
Ankle Joint Mobilization Affects Postoperative Pain Through Peripheral and Central Adenosine A1 Receptors
Daniel F. Martins, Leidiane Mazzardo-Martins, Francisco J. Cidral-Filho,Juliana Stramosk, and Adair R.S. Santos
 
The Hypothesis-Oriented Pediatric Focused Algorithm: A Framework for Clinical Reasoning in Pediatric Physical Therapist Practice
Lisa K. Kenyon